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CDC42 Antibody (OAPB00856)

CDC42 Antibody (OAPB00856)

CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Reactivities

Hum, Mouse, Rat

Presku

OAPB00856

Target

Cell division cycle 42

Alternative Names

CDC42; Cell division cycle 42; G25K

SUPPLIER INFO

Aviva Systems Biology Incorporated

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