Supplier:
Aviva Systems Biology IncorporatedCD86 (CD86 molecule ) Blocking Peptide (the C terminal of CD86)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP63007
Target
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Weight
23kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
B7-2; B70; CD28LG2; LAB72; MGC34413
SUPPLIER INFO
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