Reactivities: | Human |
Presku: | AAP63347 |
Size: | 100ug |
Weight: | 28kDa |
Gene: | 6606 |
Format: | Lyophilized powder |
Target: | SMN1 localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. |
Alternative names: | BCD541; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMN2; SMNT; T-BCD541 |