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CD80 (2A2) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252881

CD80 (2A2) Antibody

CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. Its principal mode of action is by binding to CD28. Along with CD86, these molecules provide the necessary stimuli to prime T cells against antigens presented by antigen-presenting cells. CD80 and CD86 also bind to CTLA-4, a cell surface molecule e, Xenopus/Amphibian,pressed on activated T cells. Interactions between CD80 or CD86 with CTLA-4 decrease the response of T cells.

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SPECIFICATIONS

Catalog Number

252881

Size

0.1 ml

Applications

IF

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of CD80 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

P33681

Clonality

2A2

Additional Info

T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD80; CD28LG; CD28LG1; LAB7

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