Reactivities: | Human |
Presku: | AAP63008 |
Size: | 100ug |
Weight: | 35kDa |
Gene: | 968 |
Format: | Lyophilized powder |
Target: | This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. |
Alternative names: | DKFZp686M18236; GP110; SCARD1 |