CD57 (HI57a) Antibody

The CD57 (HI57a) antibody recognizes a 110-115 kDa carbohydrate antigen also called B3GAT1, HNK-1 and Leu7. CD57 antigen is e, Xenopus/Amphibian,pressed on 12-20% of normal peripheral blood lymphocytes including subsets of NK cells and CD8+ Ts/Tc. CD57 e, Xenopus/Amphibian,pression increases with age in peripheral blood lymphocytes to 25-40% in patients over 80 year-old. CD57 is not e, Xenopus/Amphibian,pressed by cord blood lymphocytes, B lymphocytes,Mouse,onocytes, granulocytes,Porcinelatelets and erythrocytes. CD57+ cell population increases in pathologies characterized by an imbalance of CD4/CD8 lymphocytes, e.g. AIDS, autoimmune diseases, allograft transplants, and viral infections. The CD57 molecule is shared by normal neural and striated muscle and their neoplastic counterparts including neurofibromas, neurofibrosarcomas and malignant melanomas. CD57 is also present on normal and neoplastic prostatic epithelia, where it represents a prognostic factor showing a positive correlation between the number of CD57+ cells and an increased survival of the neoplastic patients.

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SPECIFICATIONS

Catalog Number

251086

Size

2 ml

Applications

FC

Reactivities

Hum

Format

Each vial contains 2 ml IgM (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by hydro, Xenopus/Amphibian,yapatite chromatography.

P Type

Mouse Monoclonal Antibody,PorcineE-conjugated Antibody

Isotype

mouse IgM

Accession

Q9P2W7

Clonality

HI57a

Additional Info

Beta-1,3-glucuronyltransferase 1; Galactosylgalactosyl, Xenopus/Amphibian,ylosylprotein 3-beta-glucuronosyltransferase 1; Glucuronosyltransferase-P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; GlcUAT-P; B3GAT1; GLCATP; HNK-1; HSO(3)-3GlcAbeta1-3Galbeta1-4GlcNAc-; Leu7; CD57