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CD45 Antibody

CD45 Antibody

Cat no: 251175

Supplier: ABBIOTEC
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The CD45 antigen (Receptor-type tyrosine-protein phosphatase C,PorcineTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. Defects in CD45 are a cause of severe combined immunodefiency autosomal recessive T-cell negative/B-cell-positive/NK-cell-positive (T-B+NK+ SCID). Genetic variations in CD45 are involved in multiple sclerosis susceptibility.
Catalogue number: 251175
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P08575
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD45.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Leukocyte common antigen; L-CA; T200; CD45 antigen; PTPRC; Receptor-type tyrosine-protein phosphatase C; CD45
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