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CD41 (HIP11) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250965

CD41 (HIP11) Antibody

The CD41 (HIP11) antibody recognizes a 140-kDa glycoprotein which is the ? subunit of the CD41/CD61 (GPIIb/IIIa, ?IIb(B)3) comple, Xenopus/Amphibian, called glycoprotein IIb (GPIIb). GPIIb is a calcium-dependent, no covalently associated heterodimer and contains a heavy chain (GPIIb?) and a light chain (GPIIb(B)) linked by a single disulfide bond. The CD41 antigen is strictly e, Xenopus/Amphibian,pressed on platelets and platelet precursors (megakaryocytes). The CD41/CD61 comple, Xenopus/Amphibian, is the receptor for fibrinogen, fibronectin and von Willebrand factor, and plays a central role in platelet activation and aggregation. The GPIIb/IIIa may be absent or strongly reduced in Glanzmann

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SPECIFICATIONS

Catalog Number

250965

Size

0.1 mg

Applications

FC, IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Isotype

mouse IgG1

Accession

P08514, NP_000410

Clonality

HIP11

Additional Info

Integrin alpha-IIb; Platelet membrane glycoprotein IIb; GPalpha IIb; GPIIb; CD41 antigen; ITGA2B; GP2B; ITGAB

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