Supplier:
Aviva Systems Biology IncorporatedCD3E (CD3e molecule, epsilon (CD3-TCR complex)) Blocking Peptide (the middle region of CD3E)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP59097
Target
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Weight
23kDa
Gene Id
916
Alternative Names
FLJ18683; T3E; TCRE
SUPPLIER INFO
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