Home  >  Products  >  CD33 (CD33 molecule ) Blocking Peptide (the N terminal of CD33)(100ug)
CD33 (CD33 molecule ) Blocking Peptide (the N terminal of CD33)(100ug)

CD33 (CD33 molecule ) Blocking Peptide (the N terminal of CD33)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-CD33 Antibody (ARP63067_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63067
Size: 100ug
Weight: 38kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
Alternative names: FLJ00391; SIGLEC-3; SIGLEC3; p67
See Full Product Listings >