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CD31 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252253

CD31 Antibody

CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is e, Xenopus/Amphibian,pressed on the surface of circulating platelets,Mouse,onocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular e, Xenopus/Amphibian,pression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31, which has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily.

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SPECIFICATIONS

Catalog Number

252253

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA and 0.02% gentamicin. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody, HRP-conjugated Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PECAM1.

Isotype

Rabbit Ig

Accession

P16284

Additional Info

Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; CPIIA'; CD31 antigen; PECAM1

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