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CD2AP Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251169

CD2AP Antibody

CD2-associated protein (CD2AP) is an adapter protein between membrane proteins and the actin cytoskeleton. CD2AP plays a role in receptor clustering and cytoskeletal polarity in the junction between T-cells and antigen-presenting cells. CD2AP anchors the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis. Defects in CD2AP are the cause of susceptibility to focal segmental glomerulosclerosis type 3 (FSGS3), a renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema.

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SPECIFICATIONS

Catalog Number

251169

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD2AP.

Isotype

Rabbit Ig

Accession

Q9Y5K6

Additional Info

CD2AP; CD2-associated protein; Cas ligand with multiple SH3 domains; Adapter protein CMS

SUPPLIER INFO

ABBIOTEC

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