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CD276 (6A1) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253062

CD276 (6A1) Antibody

CD276 is a member of Costimulatory B7 molecules, signal through CD28 family molecules such as CD28, CTLA4, and ICOS. It may participate in the regulation of T-cell-mediated immune response. It can be protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Also,Mouse,ay be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. CD276 could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytoto, Xenopus/Amphibian,ic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

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SPECIFICATIONS

Catalog Number

253062

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human CD276 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q5ZPR3

Clonality

6A1

Additional Info

CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3 Costimulatory molecule; CD276 PSEC0249; UNQ309/PRO352; B7H3; CD276

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