CD19 (HIB19) Antibody

The CD19 antibody recognizes a 95-kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is e, Xenopus/Amphibian,pressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 e, Xenopus/Amphibian,pression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. E, Xenopus/Amphibian,pression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells,Mouse,onocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes e, Xenopus/Amphibian,press CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation.