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CD18 Integrin beta-2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251165

CD18 Integrin beta-2 Antibody

CD18 Integrin beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. CD18 Integrin beta-2 is a receptor for the iC3b fragment of the third complement component and for fibrinogen. CD18 Integrin beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, binds P1 and P2 peptides of fibrinogen gamma chain, and is also a receptor for factor , Xenopus/Amphibian,. Defects in CD18 Integrin beta-2 are the cause of leukocyte adhesion deficiency type 1 (LAD1). LAD1 patients have recurrent bacterial infections and their leukocytes are deficient in a wide range of adhesion-dependent functions.

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SPECIFICATIONS

Catalog Number

251165

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD18 Integrin beta-2.

Isotype

Rabbit Ig

Accession

P05107

Additional Info

Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; MFI7; Integrin (B)2; Integrin-(B)2

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