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CD16 Monoclonal Antibody

Cat no: ABM40090

CD16 Monoclonal Antibody

FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. Fc fragment of IgG receptor IIIa encoded by FCGR3A is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in FCGR3A have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for FCGR3A.

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SPECIFICATIONS

Catalog Number

ABM40090

Size

30micro l, 100micro l, 200micro l

Applications

IHC-F, WB

Hosts

Mouse

Reactivities

Hum

Gene Id

2214/2215

Isotype

Mouse IgG1

Accession

P08637/O75015

Clonality

Monoclonal

Concentration

1 mg/ml

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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