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CD16 alpha Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250164

CD16 alpha Antibody

This antibody recognizes a polymorphism variant of CD16 alpha antigen, which is a low affinity receptor for aggregated IgG (Fc gamma receptor III). The receptor e, Xenopus/Amphibian,ists in two distinct forms: a glycosyl phosphatidyl inositol (GPI) form (Fc gamma RIIIB), and an integral membrane protein (Fc gamma RIIIA). In humans, the transmembrane form is e, Xenopus/Amphibian,pressed on NK cells and macrophages whereas the GPI-linked form is e, Xenopus/Amphibian,pressed on granulocytes. This antibody binds both forms but binds poorly to NK cells from donors not carrying the polymorphism. The antibody can be used for detecting CD16 in flow cytometry, immunoprecipitation, western blot and blocks ligand binding.

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SPECIFICATIONS

Catalog Number

250164

Size

0.1 mg

Applications

FC, WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

?

Isotype

mouse IgG1

Accession

P08637, NP_000560

Clonality

MEM154

Additional Info

Low affinity immunoglobulin gamma Fc region receptor III-A; IgG Fc receptor III-2; Fc-gamma RIII-alpha; Fc-gamma RIIIa; FcRIIIa; Fc-gamma RIII; FcRIII; FcR-10; CD16a antigen; FCGR3A; CD16A; FCG3; FCGR3; IGFR3

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