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CD14 (HI221) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250947

CD14 (HI221) Antibody

The CD14 (HI221) antibody recognizes a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein, which is found on cells of myelomonocytic lineage including monocytes (strongly), granulocytes (weakly) and also on most tissue macrophages. CD14 antigen is also present on reticular dendritic cells, some Langerhans cells, and B lymphocytes (weakly), but is absent from T lymphocytes, NK cells, erythrocytes and platelets. CD14 functions as a high affinity receptor for the comple, Xenopus/Amphibian, of lipopolysaccharide (LPS-endoto, Xenopus/Amphibian,in) and LPS-binding protein (LBP), and is the major receptor involved in the lethal response to both endoto, Xenopus/Amphibian,in and Gram-negative bacteria. In addition to membrane CD14, soluble form of CD14 can be detected in serum and tissue culture supernatants of cells transfected with CD14.

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SPECIFICATIONS

Catalog Number

250947

Size

0.1 mg

Applications

FC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgM in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by hydro, Xenopus/Amphibian,yapatite chromatography.

P Type

Mouse Monoclonal Antibody

Isotype

mouse IgM

Accession

P08571, NP_000582

Clonality

HI221

Additional Info

Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; Monocyte differentiation antigen CD14, urinary form; Monocyte fiferentiation antigen CD14,Mouse,embrane-bound form; CD14

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