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CD11b Antibody

CD11b Antibody

Cat no: 251389


Supplier: ABBIOTEC
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CD11b is involved in various adhesive interactions of monocytes,Mouse,acrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD11b is identical with CR-3, the receptor for the iC3b fragment of the third complement component. Genetic variations in CD11b have been associated with susceptibility to systemic lupus erythematosus type 6 (SLEB6). SLEB6 is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Catalogue number: 251389
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P11215
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD11b.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: CD11b; Integrin alpha-M; Leukocyte adhesion receptor MO1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Neutrophil adherence receptor; CD11 antigen-like family member B; CD11b antigen; ITGAM; CR3A