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CCR10 (chemokine (C-C motif) receptor 10 ) Blocking Peptide (the middle region of CCR10)(100ug)

CCR10 (chemokine (C-C motif) receptor 10 ) Blocking Peptide (the middle region of CCR10)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CCR10 Antibody (ARP63519_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63519
Size: 100ug
Weight: 40kDa
Gene: 2826
Format: Lyophilized powder
Target: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.
Alternative names: GPR2
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