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CCND1 (3D8) Antibody

CCND1 (3D8) Antibody

Cat no: 253019

Supplier: ABBIOTEC
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CCND1 (Cyclin D1) is a cell-cycle related protein kinase. Comple, Xenopus/Amphibian,es with CDK4 and CDK6 serine/threonine protein kinases to impart substrate specificity. Cyclin-D1 is essential for G1/S phase transition. Following DNA damage, Cyclin-D1 is phosphorylated at Thr-286 by MAP kinases, leading to its FB, Xenopus/Amphibian,O31-mediated ubiquitination and subsequent degradation. Chromosomal aberrations of CCND1 lead to various neoplastic and proliferative disorders.
Catalogue number: 253019
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: P25322
Antigen: Purified recombinant fragment of human CCND1 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 3D8
Additional info: Cyclin D1; G1/S-specific cyclin-D1; PRAD1 oncogene; BCL-1 oncogene; BCL1; PRAD1; B-cell lymphoma 1 protein; CCND1; Cyl-1
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