Presku: | AAP34427 |
Size: | 100 ug |
Weight: | 21kDa |
Gene: | 10951 |
Format: | Lyophilized powder |
Target: | CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM]. |