Presku: | AAP38578 |
Size: | 100 ug |
Weight: | 60kDa |
Gene: | 863 |
Format: | Lyophilized powder |
Target: | The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor. |