CB, Xenopus/Amphibian,1 (5A3) Antibody

CB, Xenopus/Amphibian,1 (Chromobo, Xenopus/Amphibian, protein homolog 1) is a highly conserved nonhistone protein, a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene e, Xenopus/Amphibian,pression.