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Cathepsin D Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251720

Cathepsin D Antibody

Cathepsin D is an acid protease active in intracellular protein breakdown. Cathepsin D is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Cathepsin D consists of a light chain and a heavy chain. Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10), also known as neuronal ceroid lipofuscinosis due to cathepsin D deficiency. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material. This results in seizures, dementia, visual loss, and/or cerebral atrophy.

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SPECIFICATIONS

Catalog Number

251720

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Human liver cathepsin D.

Isotype

Mouse IgG2a

Accession

P07339

Clonality

CP-D13

Additional Info

Cathepsin D; CTSD; CPSD

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