Catenin gamma Antibody

Catenin gamma is junctional plaque protein. This membrane-associated protein is an architectural element and influences the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of catenin gamma in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Defects in catenin gamma are the cause of Na, Xenopus/Amphibian,os disease (N, Xenopus/Amphibian,D). N, Xenopus/Amphibian,D is an autosomal recessive disorder combining diffuse non-epidermolytic palmoplantar keratoderma with arrhythmogenic right ventricular dysplasia/cardiomyopathy and woolly hair.