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Caspase-3 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250573

Caspase-3 Antibody

Caspase-3 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. At the onset of apoptosis, Caspase-3 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond as well as cleaving and activating the sterol regulatory element binding proteins (SREBPs) between the basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, leucine zipper domain and the membrane attachment domain. In addition Caspase-3 cleaves and activates caspase-6, -7, -9.

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SPECIFICATIONS

Catalog Number

250573

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Caspase-3.

Isotype

Rabbit Ig

Accession

P42574

Additional Info

Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Yana protein; SREBP cleavage activity 1; SCA-1; CASP3; CPP32

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