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Caspase-3 Antibody

Caspase-3 Antibody

Cat no: 250573

Supplier: ABBIOTEC
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Caspase-3 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. At the onset of apoptosis, Caspase-3 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond as well as cleaving and activating the sterol regulatory element binding proteins (SREBPs) between the basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, leucine zipper domain and the membrane attachment domain. In addition Caspase-3 cleaves and activates caspase-6, -7, -9.
Catalogue number: 250573
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P42574
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Caspase-3.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Yana protein; SREBP cleavage activity 1; SCA-1; CASP3; CPP32
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