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caspase-10 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252225

caspase-10 Antibody

Caspase-10 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. Caspase-10 is recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner, and participates in the granzyme B apoptotic pathways. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Defects in caspase-10 are a cause of familial non-Hodgkin lymphoma (NHL). NHL is a cancer that starts in cells of the lymph system, which is part of the body's immune system. NHLs can occur at any age and are often marked by enlarged lymph nodes, fever and weight loss.

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SPECIFICATIONS

Catalog Number

252225

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-10.

Isotype

Rabbit Ig

Accession

Q92851

Additional Info

Caspase-10; CASP-10; ICE-like apoptotic protease 4; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; CASP10; MCH4

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