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Caspase-1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251903

Caspase-1 Antibody

Caspase-1 is a thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Caspase-1 important for defense against pathogens. Caspase-1 cleaves and activates sterol regulatory element binding proteins (SREBPs), and also promotes apoptosis. Caspase-1 is specifically inhibited by the cowpo, Xenopus/Amphibian, virus Crma protein

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SPECIFICATIONS

Catalog Number

251903

Size

0.1 mg

Applications

IF, IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-1.

Isotype

Rabbit Ig

Accession

P29466

Additional Info

Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; IL-1 beta-converting enzyme; ICE; p45; CASP1; IL1BC; IL1BCE

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