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CASP5 (caspase 5, apoptosis-related cysteine peptidase) Blocking Peptide (the middle region of CASP5)(100ug)

CASP5 (caspase 5, apoptosis-related cysteine peptidase) Blocking Peptide (the middle region of CASP5)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CASP5 Antibody(ARP58992_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP58992
Size: 100ug
Weight: 43kDa
Gene: 838
Format: Lyophilized powder
Target: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
Alternative names: ICE(rel)III; ICEREL-III; ICH-3; MGC141966
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