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CASP4 (caspase 4, apoptosis-related cysteine peptidase) Blocking Peptide (the middle region of CASP4)(100ug)

CASP4 (caspase 4, apoptosis-related cysteine peptidase) Blocking Peptide (the middle region of CASP4)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CASP4 Antibody(ARP58990_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP58990
Size: 100ug
Weight: 10kDa
Gene: 837
Format: Lyophilized powder
Target: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Alternative names: ICE(rel)II; ICEREL-II; ICH-2; Mih1/TX; TX
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