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CASP3 (caspase 3, apoptosis-related cysteine peptidase) Blocking Peptide (the C terminal of CASP3)(100ug)

CASP3 (caspase 3, apoptosis-related cysteine peptidase) Blocking Peptide (the C terminal of CASP3)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CASP3 Antibody(ARP58987_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP58987
Size: 100ug
Weight: 12kDa
Gene: 836
Format: Lyophilized powder
Target: CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Alternative names: CPP32; CPP32B; SCA-1
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