Reactivities: | Human |
Presku: | AAP58434 |
Size: | 100ug |
Weight: | 29kDa |
Gene: | 826 |
Format: | Lyophilized powder |
Target: | Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. |
Alternative names: | 30K; CALPAIN4; CANP; CANPS; CAPN4; CDPS |