Supplier:
Aviva Systems Biology IncorporatedCALR (calreticulin) Blocking Peptide (the middle region of CALR)(100ug)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP58880
Target
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Weight
46kDa
Gene Id
811
Alternative Names
CRT; FLJ26680; RO; SSA; cC1qR
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