Supplier:
Aviva Systems Biology IncorporatedC8orf4 (chromosome 8 open reading frame 4 ) Blocking Peptide (the N terminal of C8orf4)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP65059
Target
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Weight
12kDa
Gene Id
56892
Alternative Names
MGC22806; TC-1; TC1; hTC-1
SUPPLIER INFO
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