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C2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

C2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Partial length C2 is expressed in E. coli.

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SPECIFICATIONS

Size

200ug

Presku

APL10753

Target

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Weight

40

Gene Id

717

Alternative Names

CO2; DKFZp779M0311

SUPPLIER INFO

Aviva Systems Biology Incorporated

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