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C-10 Rat - Recombinant Rat C-10 (CCL6) (2ug)

C-10 Rat - Recombinant Rat C-10 (CCL6) (2ug)

Product Introduction: Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced. CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
Product Description: C-10 Rat Recombinant produced in E.Coli is a signle, non-glycosylated, polypeptide chain containing 94 amino acids and having a total molecular mass of 10.4kDa. C-10 is purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

2ug

Format

Sterile Filtered White lyophilized (freeze-dried) powder.

Presku

OOPA00018

Alternative Names

Small inducible cytokine A6; CCL6; C10 protein; c10; MRP-1; Scya6; chemokine (C-C motif) ligand 6.

SUPPLIER INFO

Aviva Systems Biology Incorporated

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