Supplier:
Alomone Labs Limited.Cat no: RTA-500
BUY omega-Agatoxin IVA
NativeпїЅomega- Agatoxin IVAпїЅwas originally isolated fromпїЅAgelenopsis apertaпїЅspider venom, and was shown to be a selective blocker of Cav2.1 (P/Q type) channels. However, the sensitivity depends on the auxiliaryпїЅbetaпїЅsubunit isoformпїЅand on the splice variant. Therefore, the effective concentrationпїЅvaries between systems. In accordance, the toxin blocks presynaptic Ca2+пїЅcurrents and synaptic transmission in a variety of synapses.
omega-Agatoxin IVA is widely used in electrophysiological measurements of cloned and native channels. It is used to assess the role of Cav2.1 channels in synaptic transmission. In addition it was used to map the spatial distribution of Cav2.1 channels in mouse cerebellar and hippocampal brain slices.
Ion Channel Modulators; Voltage - Gated Ca2+пїЅChannel Blockers.
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SPECIFICATIONS
Catalog Number
RTA-500
Size
5 x 10 micro g
Purity
>99%
Concentration
20 nM - 1 micro M.
Shipping Temp
Room Temperature
Molecular Weight
5333.4 da
SUPPLIER INFO
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