Supplier:
Alomone Labs Limited.Cat no: STG-100
BUY GsMTx-4
A Blocker of Voltage-Gated \\v\\1.7 Na\\+\\Channels.
This product is not for sale in the United States of America.
GsMTX-4 is a 34 amino acid peptidyl toxin isolated from the Grammostola rosea (Chilean rose) tarantula venom and belongs to the huwentoxin-1 family.
This toxin inhibits different channels and in addition has antimicrobial activity. It blocks cation-selective mechanosensitive ion channels (strech-activated channels, SACs), without having effect on whole-cell voltage-sensitive currents.
In addition, it inhibits atrial fibrillation as well as the membrane motor of outer hair cells at low doses. A medium toxicity on a large spectra of voltage-gated Na\\+\\channels, namely \\v\\1.1, \\v\\1.2, \\v\\1.3, \\v\\1.4, \\v\\1.5, \\v\\1.6 and \\v\\1.7 was reported.
GsMTx-4 also inhibits K\\+\\ channels K\\v\\11.1 and K\\v\\11.2, whereas it does not inhibit K\\+\\ channels K\\V\\1.1 (ICK\\50\\ > 85 μM), K\\V\\1.4 (ICK\\50\\ > 85 μM) and K\\V\\11.3 (ICK\\50\\ = 53 μM).
GsMTX-4 was also found to inhibit both TRPC1 and TRPC6 channels.
Antimicrobial activity is shown against several Gram-positive and Gram-negative bacteria as well.
Ion Channel Modulators; Voltage - Gated Na+ Channel Blockers, TRP Channel Modulators
Prices direct from Alomone Labs Limited.
Quick response times
Exclusive Absave savings/discounts
SPECIFICATIONS
Catalog Number
STG-100
Size
50 micro g
Purity
>98 %
Concentration
500 nM - 10 uM
Shipping Temp
Room Temperature
Molecular Weight
4096 da
SUPPLIER INFO
Latest promotions
New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...
Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...
We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!
For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...
10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...
Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...
Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...
Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...
Top suppliers
Agrisera AB
11 products
Biotrend
Biosensis
969 products
ABBIOTEC
3011 products
SDIX
1 products
Spring Bioscience
2291 products
Cell Signaling Technology
4976 products
Rockland Immunochemicals, Inc.
7592 products
Boster Immunoleader
1533 products
Proteintech Group
1 products
OriGene Technologies Inc.
5281 products
Maine Biotechnology Services
227 products
BD (Becton, Dickinson and Company)
1 products
ABNOVA CORPORATION
Randox Life Sciences
1502 products
