Supplier:
Alomone Labs Limited.Cat no: C-330
BUY Camptothecin
Camptothecin converts topoisomerase into a cell poison by trapping the cleavable covalent complex of enzyme with duplex DNA and blocking the re-ligation step. Thereby enhancing and stabilizing the formation of DNA breakage which is responsible for cell death.
Camptothecin inhibits (IC50= 30 nM) Tat protein-mediated transactivation of HIV-1 and enhances 5/PKC??alpha activity during apoptosis in HL60 myeloid leukemia cells via a caspase-regulated mechanism. Cell Signaling Activators and Inhibitors; Topoisomerase Inhibitors, Anticancer Compounds, Apoptosis Inducers.
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SPECIFICATIONS
Catalog Number
C-330
Size
5 x 250 mg
Purity
>99%
Concentration
1-300 nM
Shipping Temp
Room Temperature
Molecular Weight
348.36
SUPPLIER INFO
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