Supplier:
Alomone Labs Limited.Cat no: STC-300
BUY alpha -Conotoxin AuIB
alpha -Conotoxin AuIB is a 15 amino acid peptidyl toxin isolated from Conus aulicus.
This toxin inhibits mammalian neuronal alpha3/beta4 nicotinic acetylcholine receptor (nAChR) channels expressed in Xenopus oocytes with an IC \\50\\ of 0.75 μM. Furthermore, alpha-Conotoxin AuIB blocks the alpha3/ beta4 receptor with >100-fold higher potency than other receptor subunit combinations.
In accordance, alpha-Conotoxin AuIB (1-5 mM) blocks 20-35% of the nicotine-stimulated norepinephrine release from rat hippocampal synaptosomes and the nicotinic ACh receptors on dissociated neurons of the rat parasympathetic ganglia with IC \\50\\ of 1.2 nM.
Ion Channel Modulators; Nicotinic Acetylcholine Receptor Channel Blockers.
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SPECIFICATIONS
Catalog Number
STC-300
Size
5 x 0.5 mg
Purity
>99%
Concentration
0.1 micro M - 5 micro M
Shipping Temp
Room Temperature
Molecular Weight
1572 da
SUPPLIER INFO
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