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BTBD12 (BTB (POZ) domain containing 12) Blocking Peptide (the N terminal of BTBD12)(100ug)

BTBD12 (BTB (POZ) domain containing 12) Blocking Peptide (the N terminal of BTBD12)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-BTBD12 Antibody (ARP59857_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP59857
Size: 100ug
Weight: 200kDa
Gene: 84464
Format: Lyophilized powder
Target: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.
Alternative names: KIAA1784; KIAA1987; MUS312; SLX4
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