Brilliant Violet 510(TM) anti-mouse CD11c

CD11c is a 150 kD glycoprotein also known as alphaX integrin, CR4, and p150. CD11c forms a alphaXbeta2 heterodimer with beta2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The alphaXbeta2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

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SPECIFICATIONS

Catalog Number

117338

Size

500 microl

Applications

FC

Hosts

Ham

Reactivities

Mouse

Clone

N418

Antigen

Mouse spleen dendritic cells

Gene Id

16411

Isotype

Armenian Hamster IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.Brilliant Violet 510(TM) excites at 405 nm and emits at 510 nm. The bandpass filter 510/50 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 510(TM) is a trademark of Sirigen Group Ltd.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

alphaX integrin chain, alphaXbeta2, CR4, p150, alpha integrin, alphaX integrin, alpha X integrin, aX integrin, integrin alphaX, integrin aX, integrin alpha X

Regulatory Status

RUO