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Brilliant Violet 421(TM) anti-human CD122 (IL-2Rbeta)

Brilliant Violet 421(TM) anti-human CD122 (IL-2Rbeta)

Cat no: 339010

Supplier: BioLegend
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CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor beta chain also known as IL-2Rbeta, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rbeta chain can combine with either the common gamma subunit (gammac, CD132) alone or with the gammac subunit and the IL-2Ralpha subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.
Catalogue number: 339010
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 tests
Clone: TU27
Gene: 3560
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.Brilliant Violet 421(TM) excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421(TM) is a trademark of Sirigen Group Ltd.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: TL-Mor cell line
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: IL-2 Receptor beta chain, IL-2Rbeta, IL-2Rbeta
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