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BPNT1 Human - Recombinant Human 3(2) 5-Bisphosphate Nucleotidase 1 (2ug)

BPNT1 Human - Recombinant Human 3(2) 5-Bisphosphate Nucleotidase 1 (2ug)


Supplier: Aviva Systems Biology Incorporated
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Product Introduction: BPNT1 belongs to the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate) using magnesium as a cofactor. BPNT1 is expressed everywhere but at maximum levels in brain and kidney. BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, which suggests that BPNT1 has a possible role in the etiology of mood disorders.
Product Description: BPNT1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 344 amino acids (1-308a.a.) and having a molecular mass of 37.5kDa. BPNT1 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Presku: OOPA00078
Size: 2ug
Format: Sterile Filtered clear solution.
Alternative names: 3'(2'); 5'-bisphosphate nucleotidase 1; Bisphosphate 3'-nucleotidase 1; PAP-inositol-1;4-phosphatase; PIP; EC 3.1.3.7; BPntase.