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Bmp10 (bone morphogenetic protein 10) Blocking Peptide (the N terminal of Bmp10)(100ug)

Bmp10 (bone morphogenetic protein 10) Blocking Peptide (the N terminal of Bmp10)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Bmp10 Antibody(ARP47031_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Rat
Presku: AAP47031
Size: 100ug
Weight: 48kDa
Gene: 500245
Format: Lyophilized powder
Target: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
Alternative names: Bmp10
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