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Bmi1 (Bmi1 polycomb ring finger oncogene ) Blocking Peptide (the middle region of Bmi1)(100ug)

Bmi1 (Bmi1 polycomb ring finger oncogene ) Blocking Peptide (the middle region of Bmi1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Bmi1 Antibody (ARP33655_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP33655
Size: 100ug
Weight: 37kDa
Gene: 12151
Format: Lyophilized powder
Target: Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Alternative names: AW546694; Bmi-1; Pcgf4
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