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BLK (9D10) Antibody

BLK (9D10) Antibody

Cat no: 252670


Supplier: ABBIOTEC
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BLK (B lymphoid tyrosine kinase) is a 505-amino acid protein (~56KDa), belongs to the Src non-receptor tyrosine kinases family. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. Blk is e, Xenopus/Amphibian,pressed e, Xenopus/Amphibian,clusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid e, Xenopus/Amphibian,pression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
Catalogue number: 252670
Reactivities: Human
Applications: Immunohistochemistry
Size: 0.1 ml
Accession: P51451
Antigen: Purified recombinant fragment of BLK e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 9D10B7H6?9D10A8F8
Additional info: Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk; BLK