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Biotin anti-mouse Notch 4

Biotin anti-mouse Notch 4

Cat no: 128404

Supplier: BioLegend
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The Notch receptors and their ligands are highly conserved from invertebrates to mammals. The Delta-like 1 (Dll1) is one of the four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process. Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice and engagement of Notch 1 by Dll 1 promotes differentiation of B lymphocytes to antibody-secreting cells.
Catalogue number: 128404
Reactivities: Mouse
Hosts: Hamster
Applications: Flow Cytometry, Immunohistochemistry
Conjugates: Biotin
Size: 500 microg
Clone: HMN4-14
Gene: 18132
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: Notch4-Fc recombinant protein
Isotype: Armenian Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Int3, Int-3, Neurogenic locus notch homolog protein 4 precursor, Notch-4
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