Biotin anti-human IL-4

IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

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SPECIFICATIONS

Catalog Number

500804

Size

500 microg

Applications

FC, ICC

Hosts

Rat

Reactivities

Hum

Conjugates

Biotin

Clone

MP4-25D2

Antigen

CHO-expressed, recombinant human IL-4

Gene Id

3565

Isotype

Rat IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 0.25-1.0 microg/ml is recommended. To obtain a linear standard curve, serial dilutions of human IL-4 protein ranging from 500 to 2 pg/ml are recommended for each ELISA plate.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. Do not freeze.

Alternative Names

Interleukin-4, IaIF, BSF-1, HCGF, MCGF-2, MFF, TCGF-2

Regulatory Status

RUO